ARHGDIB

(Rho GDP dissociation inhibitor (GDI) beta)

 

  • Alias                                 (According to NCBI)

 
  • D4;
  • GDIA2;
  • GDID4;
  • LYGDI;
  • Ly-GDI;
  • RAP1GN1
  • Rho GDP dissociation inhibitor (GDI) beta
  • Rho GDI 2

  • Regulates the GDP/GTP exchange reaction of the Rho proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them.
  • Location: 12p12.3
  • Size: 19613 bp
  • exons: 5
  • DNA sequence (Human): NC_000012.10

  • CGH (8q22):  Losses (%) -5.0   Gain (%)  7.3
  • Mutations and SNPs (According to HGMD and SNP)

 
  • HGMD :
  • SNPs:

 
  • m-RNA                       (According to NCBI and CGAP)

 

  • mRNA sequence (Human):  NM_001175.4

  • Size: 1216 bp

  • cDNA libraries:

  • Size: 201 amino acids: 22988 Da

  • Subcellular location: Cytoplasm

  • Protein domains

     

 

  • Pathway:

                        

  • Clinical                            (According to OMIM, PubMed)