CRABP2

(Cellular Retinoic Acid Binding Protein 2)

 

  • Alias                                 (According to NCBI)

 
  • RBP6; 
  • Retinoic acid-binding protein II, cellular
  • CRABP-II
  • Transports retinoic acid to the nucleus. Regulates the access of retinoic acid to the nuclear retinoic acid receptors.
  • Location: 1q21.3
  • Size: 5973 bp
  • exons: 4
  • DNA sequence (Human): NC_000001

  • CGH (8q22):  Losses (%) -1.1   Gain (%)  7.3  

  • Mutations and SNPs (According to HGMD and SNP)

 

 
  • m-RNA                       (According to NCBI and CGAP)

 
  • Size: 138 amino acids; 15693 Da

  • Subcellular location: Cytoplasm. Nucleus. Note=Upon ligand binding, a conformation change exposes a nuclear localization motif and the protein is transported into the nucleus.

  • Protein domains

     

  • Pathways and interactions (According to Kegg, PIR)

 

                        

  • Protein interactions: CRABP2
  • Clinical                            (According to OMIM, PubMed)