CSF1R

(Colony stimulating factor 1 receptor)

 

  • Alias                                 (According to NCBI)

 
  • C-FMS,
  • CD115,
  • CSFR,
  • FIM2,
  • FMS
  • CD115 antigen;
  • FMS proto-oncogene;
  • colony stimulating factor 1 receptor;
  • macrophage colony stimulating factor I receptor
  • This protein is the receptor for CSF-1, it is a protein tyrosine-kinase transmembrane receptor.
  • Location: 5q33-q35
  • Size:60078 bp
  • exons: 14
  • DNA sequence (Human): NC_000005

  • CGH (8q22):  Losses (%) -15.1   Gain (%)  3.4  

  • Mutations and SNPs (According to HGMD and SNP)

 

 
  • m-RNA                       (According to NCBI and CGAP)

 

  • mRNA sequence (Human):  NM_005211

  • Size: 3985 bp

  • cDNA libraries: CSF1R
  • Size: 972 amino acids; 107984 Da
  • Subunit: Interacts with INPPL1/SHIP2 and THOC5

  • Subcellular location: Membrane; Single-pass type I membrane protein.

  • Protein domains

     

  • Pathways and interactions (According to Kegg, PIR)

 

                        

  • Protein interactions: CSF1R
  • Clinical                            (According to OMIM, PubMed)