DCUN1D1

(DCN1, defective in cullin neddylation 1, domain containing 1 (S. cerevisiae))

 

  • Alias                                 (According to NCBI)

 

  • DCUN1L1,
  • RP42,
  • SCCRO,
  • SCRO,
  • Tes3
  • RP42 homolog;
  • squamous cell carcinoma-related oncogene
  • May contribute to neddylation of cullin components of SCF-type E3 ubiquitin ligase complexes. Neddylation of cullins play an essential role in the regulation of SCF-type complexes activity
  • Location: 3q26.3
  • Size: 37768 bp
  • exons: 6
  • DNA sequence (Human): NC_000003.10

  • CGH (3q26.3):  Losses (%) -1.7   Gain (%)  33.5  

  • Mutations and SNPs (According to HGMD and SNP)

 

 

  • m-RNA                       (According to NCBI and CGAP)

 

  • mRNA sequence (Human):  NM_020640.2

  • Size:  3192 bp

  • cDNA libraries:

  • Size: 259 amino acids: 30124 Da
  • Protein domains

     

  • Protein sequence (Human): Q96GG9

  • Homologous genes:  10773

  • 2D PAGE:

  • 3D Structure:  

  • PTM:

 

  • Pathway:

                        

  • Clinical                            (According to OMIM, PubMed)