DEFA1

(Defensin, alpha 1)

 

  • Alias                                 (According to NCBI)

 
  • DEF1,
  • DEFA2,
  • HNP-1,
  • HP-1,
  • MGC138393,
  • MRS
  • defensin, alpha 1, myeloid-related sequence;
  • defensin, alpha 2; myeloid-related sequence
  • Defensins 1/2 have antibiotic, fungicide and antiviral activities.
  • Location: 8p23.1
  • Size:15908 bp
  • exons: 2
  • DNA sequence (Human): NC_000008.9

  • CGH (8p23.1):  Losses (%) -39.1   Gain (%) 3.9    Amplifications  0.0

  • Mutations and SNPs (According to HGMD and SNP)

 

 
  • m-RNA                       (According to NCBI and CGAP)

 

  • mRNA sequence (Human):  NM_004084.2

  • Size: 490 bp

  • cDNA libraries:

  • Size: 94 amino acids: 10201 Da
  • Catalytic activity:

  • Subcellular location: Secreted

  • Protein domains

     

 

  • Pathway:

                        

  • Protein interactions: DEFA1
  • Clinical                            (According to OMIM, PubMed)