DEFA3

(Defensin,alpha 3, neutrophil-specific)

 

  • Alias                                 (According to NCBI)

 
  • DEF3,
  • HNP-3,
  • HNP3,
  • HP-3
  • defensin 3, neutrophil-specific;
  • defensin, alpha 3;
  • neutrophil peptide 3
  • Defensins 3/2 have antibiotic, fungicide and antiviral activities.
  • Location: 8pter-p23.3
  • Size: 2422 bp
  • exons: 2
  • DNA sequence (Human): NC_000008.9

  • CGH (8q22):  Losses (%) -15.0   Gain (%)  3.8  

  • Mutations and SNPs (According to HGMD and SNP)

 

 
  • m-RNA                       (According to NCBI and CGAP)

 

  • mRNA sequence (Human):  NM_005217.2

  • Size: 487 bp

  • cDNA libraries:

  • Size: 95 amino acids: 10245 Da
  • Catalytic activity:

  • Subcellular location: Secreted

  • Protein domains

     

 

  • Pathway:

                        

  • Protein interactions:

  • Clinical                            (According to OMIM, PubMed)