FABP5

(Fatty acid binding protein-5)

 

  • Alias                                 (According to NCBI)

 
  • EFABP (Psoriasis associated)
  • E-FABP
  • PAFABP
  • PA-FABP
  • High specificity for fatty acids. Highest affinity for C18 chain length. Decreasing the chain length or introducing double bonds reduces the affinity. May be involved in keratinocyte Specific for differentiation.Keratinocytes; highly expressed in psoriatic skin.htey are involved in fatty acid uptake, transport, and metabolism.
  • Location: 8q21.13
  • Size:   4224 bp
  • exons: 4
  • DNA sequence (Human): NC_000008.

  • CGH (8q21.13):  Losses (%) -0.6   Gain (%)  29.6  

  • Mutations and SNPs (According to HGMD and SNP)

 

 
  • m-RNA                       (According to NCBI and CGAP)

 
  • Size:   135 amino acids;   15164 Da

  • Subcellular location: cytoplasm

  • Protein domains

     

  • Pathways and interactions (According to Kegg, DIP)

                                   

  • Protein interactions: FABP5
  • Clinical                            (According to OMIM, PubMed)