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- AP-1,
- C-FOS
- FBJ murine osteosarcoma viral (v-fos) oncogene homolog (oncogene FOS);
- activator protein 1;
- cellular oncogene c-fos
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- Nuclear phosphoprotein which forms a tight but non-covalently linked complex with the
JUN/AP-1 transcription factor. In the heterodimer, c-fos and JUN/AP-1 basic regions each
seems to interact with symmetrical DNA half sites. Has a critical function in regulating
the development of cells destined to form and maintain the skeleton. It is thought to have
an important role in signal transduction, cell proliferation and differentiation.
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- Location: 14q24.3
- Size:3383 bp
- exons: 4
- DNA sequence (Human): NC_000014.7
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- Mutations and SNPs (According
to HGMD and SNP)
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