HINT1

(Histidine triad nucleotide-binding protein 1)

 

  • Alias                                 (According to NCBI)

 
  • Histidine triad nucleotide-binding protein 1
  • HINT1
  • PKCI-1(Protein kinase C Interacting protein)
  • PRKCNH1

  • Hydrolyzes adenosine 5'-monophosphoramidate substrates such as AMP-morpholidate, AMP-N-alanine methyl ester, AMP-alpha-acetyl lysine methyl ester and AMP-NH2

  • Location: 5q31.2
  • Size: 6160 bp
  • exons:
  • DNA sequence (Human):  NC_000005.9

  • CGH (5q31.2):  Losses (%) -10.6   Gain (%) 3.4    

  • Mutations and SNPs (According to HGMD and SNP)

 

 
  • m-RNA                       (According to NCBI and CGAP)

 

  • mRNA sequence (Human):  NM_005340.5

  • Size: 1507 bp

  • cDNA libraries:
  • Size: 126 amino acids; 13802 Da
  • Catalytic activity:

  • Subcellular location: Cytoplasm, Nucleus

  • Protein domains

     

  • Protein sequence (Human): P49773

  • Homologous genes:

  • 2D PAGE:

  • 3D Structure: 1AV5

  • PTM:

  • Pathways and interactions (According to BioCarta, DIP)

  • Pathway:

  • Protein interactions: P49773
  • Clinical                            (According to OMIM, PubMed)