LAMA5

(Laminin, alpha 5)

 

  • Alias                                 (According to NCBI)

 
  • KIAA1907
  • laminin alpha-5 chain
  • Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components
  • Location: 20q13.2-q13.3
  • Size: 58248 bp
  • exons: 22
  • DNA sequence (Human): NC_000020

  • CGH (20q13.2):  Losses (%) -5.0   Gain (%)  19.0  

  • Mutations and SNPs (According to HGMD and SNP)

 

 
  • m-RNA                       (According to NCBI and CGAP)

 

  • mRNA sequence (Human):  NM_005560

  • Size: 11426 bp

  • cDNA libraries: LAMA5
  • Size: 500 amino acids; 54857 Da
  • Catalytic activity:

  • Subcellular location: Secreted, extracellular space, extracellular matrix, basement membrane. Note=Major component.

  • Protein domains

     

  • Pathways and interactions (According to BioCarta, DIP)

 

                        

  • Protein interactions:

  • Clinical                            (According to OMIM, PubMed)