LRP12

(low density lipoprotein-related protein 12)

 

  • Alias                                 (According to NCBI)

 

  
  • DKFZp781F1053,
  • FLJ12929,
  • ST7
  • C820005L12Rik;
  •  suppression of tumorigenicity

 
  • Probable receptor, which may be involved in the internalization of lipophilic molecules and/or signal transduction. May act as a tumor suppressor.
  • Location: 8q22.2-q23.1
  • Size: 99705 bp
  • exons: 7
  • DNA sequence (Human): NC_000008.9

  • CGH (8q22.2):  Losses (%) -0.0   Gain (%)  33.5  

  • Mutations and SNPs (According to HGMD and SNP)

 

 
  • m-RNA                       (According to NCBI and CGAP)

 

  • mRNA sequence (Human):  NM_013437.2

  • Size: 4083 bp

  • cDNA libraries:

  • Size: 859 amino acids; 94984 Da
  • Catalytic activity:

  • Subcellular location: Membrane; Single-pass type I membrane protein. Membrane, coated pit.

  • Protein domains

     

  • Protein sequence (Human): Q9Y561

  • Homologous genes:  8384

  • 2D PAGE:

  • 3D Structure:  

  • PTM: LRP12

 

  • Pathway:

                        

  • Protein interactions: LRP12
  • Clinical                            (According to OMIM, PubMed)