PEBP1

(Phosphatidylethanolamine-binding protein 1)

 

  • Alias                                 (According to NCBI)

 
  • Phosphatidylethanolamine-binding protein 1
  • PBP
  • HCNP
  • PEBP
  • RKIP (Raf kinase inhibitor protein)
  • PEBP1

  • Binds ATP, opioids and phosphatidylethanolamine. Has lower affinity for phosphatidylinositol and phosphatidylcholine. Serine protease inhibitor which inhibits thrombin, neuropsin and chymotrypsin but not trypsin, tissue type plasminogen activator and elastase.

  • Location: 12q24.23
  • Size: 9521 bp
  • exons:
  • DNA sequence (Human):  NC_000012.11

  • CGH (12q24.23):  Losses (%) -2.8   Gain (%) 4.5    

  • Mutations and SNPs (According to HGMD and SNP)

 

 
  • m-RNA                       (According to NCBI and CGAP)

 

  • mRNA sequence (Human):  NM_002567.2

  • Size: 1507 bp

  • cDNA libraries:
  • Size: 187 amino acids; 21057 Da
  • Catalytic activity:

  • Subcellular location: Cytoplasm

  • Protein domains

     

  • Protein sequence (Human): P30086

  • Homologous genes:

  • 2D PAGE: P30086

  • 3D Structure: 1BEH

  • PTM:

  • Pathways and interactions (According to BioCarta, DIP)

  • Pathway:

  • Protein interactions: P30086
  • Clinical                            (According to OMIM, PubMed)