POSTN

(periostin, Osteoblast specific factor)

 

  • Alias                                 (According to NCBI)

 

  
  • PN;
  • OSF-2;
  • PDLPOSTN;
  • MGC119510;
  • MGC119511;
  • periostin;
  • RP11-412K4.1
  • periodontal ligament-specific periostin
  • osteoblast specific factor 2 (fasciclin I-like)
  • Binds to heparin. Induces cell attachment and spreading and plays a role in cell adhesion.
  • Location: 13q13.3
  • Size: 36096 bp
  • exons: 21
  • DNA sequence (Human): NC_000013.9

  • CGH (13q13.3):  Losses (%) -9.5   Gain (%)  2.2  

  • Mutations and SNPs (According to HGMD and SNP)

 

 
  • m-RNA                       (According to NCBI and CGAP)

 

  • mRNA sequence (Human):  NM_006475.1

  • Size: 3213 bp

  • cDNA libraries:

  • Size: 836 amino acids: 93314 Da
  • Catalytic activity:

  • Subcellular location: Secreted, extracellular space, extracellular matrix.

  • Protein domains

     

  • Protein sequence (Human): Q15063

  • Homologous genes:  4730

  • 2D PAGE:

  • 3D Structure:  

  • PTM: POSTN

 

  • Pathway:

                        

  • Protein interactions:

  • Clinical                            (According to OMIM, PubMed)