PTMA

(Prothymosin, alpha)

 

  • Alias                                 (According to NCBI)

 
  • MGC104802,
  • TMSA
  • gene sequence 28;
  • prothymosin alpha protein;
  • prothymosin, alpha (gene sequence 28);
  • region containing prothymosin, alpha (gene sequence 28);
  • prothymosin, alpha (gene sequence 28);
  • prothymosin, alpha (gene sequence 28);
  • hypothetical protein MGC12250;
  • prothymosin, alpha (gene sequence 28)
  • Prothymosin alpha may mediate immune function by conferring resistance to certain opportunistic infections.

     
  • Location: 2q35-q36
  • Size: 5017 bp
  • exons: 5
  • DNA sequence (Human): NC_000002.10

  • CGH (2q35):  Losses (%) -6.7   Gain (%)  4.5 

  • Mutations and SNPs (According to HGMD and SNP)

 

 
  • m-RNA                       (According to NCBI and CGAP)

 
  • Size: 111 amino acids: 12203 Da
  • Catalytic activity:

  • Subcellular location: Nucleus.

  • Protein domains

     

  • Protein sequence (Human): P06454

  • Homologous genes:  37689

  • 2D PAGE:

  • 3D Structure:  

  • PTM: PTMA (Covalently linked to a small RNA of about 20 nucleotides. )

 

  • Pathway:

                        

  • Protein interactions: PTMA
  • Clinical                            (According to OMIM, PubMed)