• Alias                                 (According to NCBI)

• DKFZP564B163,
• RAB1,
• YPT1
• GTP binding protein Rab1a;
• RAB1, member RAS oncogene family;
• Rab GTPase YPT1 homolog

• Description   

  (According to SwissProt)

• Probably required for transit of protein from the ER through Golgi compartment. Binds GTP and GDP and possesses intrinsic GTPase activity.

• Chromosomal location

  (According to NCBI, CGH: progenetix)

• Location: 2p14
• Size: 43301 bp
• exons:
• DNA sequence (Human): NC_000002.10

• CGH (2p14):  Losses (%) -1.7   Gain (%)  5.0  

• Mutations and SNPs (According to HGMD and SNP)

• HGMD :
• SNPs: 5861

• m-RNA                       (According to NCBI and CGAP)

• mRNA sequence (Human):  NM_004161.3

• Size: 2496 bp

• cDNA libraries: RAB1A

• Protein                        (According to SwissProt, Swiss2D, PDB, dbPTM)

• Size:205 amino acids; 22678 Da
• Catalytic activity:

• Subcellular location: Golgi apparatus.

• Protein domains

• Protein sequence (Human): P62820

• Homologous genes:  36154

• 2D PAGE: RAB1A

• 3D Structure:  2FOL

• PTM: RAB1A (Phosphorylated by CDC2 kinase during mitosis)

• Pathways and interactions (According to BioCarta, Intact)

• Pathway:

         Rab GTPases mark targets in the endocytic machinery

• Protein interactions: RAB1A

• Tissue

  (According to GeneNote, PubMed, HPA)

• Tissue expression: PubMed Reference
• Human Protein Atlas (HPA): CAB005331

• Clinical                            (According to OMIM, PubMed)

• OMIM : 179508
• PubMed:    Early detection      Diagnosis         Prognosis        Therapy