S100A11

(S100 calcium binding protein A11)

 

  • Alias                                 (According to NCBI)

 
  • MLN70,
  • S100C
  • S100 calcium binding protein A11 (calgizzarin);
  • S100 calcium-binding protein A11 (calgizzarin);
  • calgizzarin
  • The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in motility, invasion, and tubulin polymerization. Chromosomal rearrangements and altered expression of this gene have been implicated in tumor metastasis.
  • Location: 1q21
  • Size: 4530 bp
  • exons: 2
  • DNA sequence (Human): NC_000001.9

  • CGH (1q21):  Losses (%) -1.1   Gain (%)  7.8  

  • Mutations and SNPs (According to HGMD and SNP)

 

 
  • m-RNA                       (According to NCBI and CGAP)

 

  • mRNA sequence (Human):  NM_005620.1

  • Size: 595 bp

  • cDNA libraries:

  • Size: 105 amino acids: 11740  Da
  • Protein domains

     

 

  • Pathway:

                        

  • Clinical                            (According to OMIM, PubMed)