SMARCA4

(SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4)

 

  • Alias                                 (According to NCBI)

 
  • BAF190,
  • BRG1,
  • FLJ39786,
  • SNF2, SNF2-BETA,
  • SNF2L4,
  • SNF2LB,
  • SWI2,
  • hSNF2b
  • BRM/SWI2-related gene 1;
  • SNF2-like 4;
  • SWI/SNF-related matrix-associated actin-dependent regulator of chromatin a4;
  • brahma protein-like 1;
  • global transcription activator homologous sequence;
  • homeotic gene regulator;
  • mitotic growth and transcription activator;
  • nuclear protein GRB1;
  • sucrose nonfermenting-like 4
  • Transcriptional coactivator cooperating with nuclear hormone receptors to potentiate transcriptional activation.
  • Location: 19p13.2
  • Size: 101348 bp
  • exons: 24
  • DNA sequence (Human): NC_000019

  • CGH (19p13.2):  Losses (%) -2.8   Gain (%)  13.4  

  • Mutations and SNPs (According to HGMD and SNP)

 

 
  • m-RNA                       (According to NCBI and CGAP)

 
  • Size: 1647 amino acids; 184646 Da
  • Catalytic activity:

  • Subcellular location: Nucleus

  • Protein domains

     

  • Pathways and interactions (According to BioCarta, DIP)

 

  • Pathway:

                        

  • Clinical                            (According to OMIM, PubMed)