SNAI1

(Snail homolog 1)

 

  • Alias                                 (According to NCBI)

 

  
  • SLUGH2,
  • SNA,
  • SNAH,
  • dJ710H13.1
  • snail 1 (drosophila homolog),
  • zinc finger protein;
  • snail 1 homolog;
  • snail 1 zinc finger protein
  • Seems to be involved in embryonic mesoderm formation. Binds to 3 E-boxes of the E-cadherin gene promoter and represses its transcription.+
  • Location: 20q13.1-q13.2
  • Size: 5897 bp
  • exons: 3
  • DNA sequence (Human): NC_000020.9

  • CGH (20q13.1):  Losses (%) -1.7   Gain (%)  17.3  

  • Mutations and SNPs (According to HGMD and SNP)

 

 
  • m-RNA                       (According to NCBI and CGAP)

 
  • Size: 264 amino acids; 29083 Da
  • Catalytic activity:

  • Subcellular location: Nucleus

  • Protein domains

     

  • Protein sequence (Human): O95863

  • Homologous genes:  4363

  • 2D PAGE: SNAI1

  • 3D Structure:  

  • PTM:

  • Pathways and interactions (According to Kegg,  IntAct)

 

  • Pathway: hsa04520  Adherens junction

                        

  • Protein interactions: SNAI1
  • Clinical                            (According to OMIM, PubMed)