TACSTD1

(Tumor Associated Calcium Signal TransDucer 1)

 

  • Alias                                 (According to NCBI)

 
  • EGP -epithelial glycoprotein
  • KSA 
  • M4S1 
  • MK-1 
  • CD326 
  • EGP40 
  • MIC18
  • TROP1
  • Ep-CAM-epithelial cell calium adhesion molecule
  • hEGP-2-human epithelial gylcoprotein
  • CO17-1A
  • SGA733-2
  • TACD1
  • M1S2
  • M4S1
  • GA733 tumor-associated antigen gene family may function as growth factor receptors and is a calcium indepentdent cell adhesion molecule.This protein is expressed in almost all epithelial cell membranes but not on mesodermal or neural cell membranes. Found on the surface of adenocarcinomas.
  • Location: 2p21
  • Size: 17691 bp
  • exons: 9
  • DNA sequence (Human):  NC_000002. 

  • CGH (2p21):  Losses (%) -2.2   Gain (%)  5.6  

  • Mutations and SNPs (According to HGMD and SNP)

 

 
  • m-RNA                       (According to NCBI and CGAP)

 
  • Size:314 amino acids; 34932 Da
  • Catalytic activity:

  • Subcellular location: Membrane; Single-pass type I membrane protein.

  • Protein domains

     

  • Pathway:

  • Clinical                            (According to OMIM, PubMed)