TNNT1

(Troponin T)

 

  • Alias                                 (According to NCBI)

 

  • Troponin T type 1
  • ANM
  • TNT
  • STNT
  • TNTS
  • Troponin T is the tropomyosin-binding subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity.

     

  • Location: 19q13.4
  • Size: 16446 bp
  • exons:
  • DNA sequence (Human):  NC_000019.9

  • CGH (19q13.4):  Losses (%) -2.2   Gain (%) 10.1  

  • Mutations and SNPs (According to HGMD and SNP)

 

 

  • m-RNA                       (According to NCBI and CGAP)

 

  • Size: 278 amino acids; 32948 Da
  • Catalytic activity:
  • Subcellular location:

  • Protein domains

     

  • Protein sequence (Human): P13805

  • Homologous genes:

  • 2D PAGE:

  • 3D Structure:

  • PTM: TNNT1

  • Pathways and interactions (According to BioCarta, DIP)
  • Pathway:

  • Protein interactions: P13805

  • Clinical                            (According to OMIM, PubMed)