TUBB2C

(Tubulin, beta 2C)

 

  • Alias                                 (According to NCBI)

 
  • RP13-122B23.2,
  • TUBB2
  • class IVb beta tubulin; tubulin, beta, 2
  • Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha-chain.
  • Location: 9q34
  • Size: 2441 bp
  • exons: 4
  • DNA sequence (Human): NC_000009.10

  • CGH (9q34):  Losses (%) -3.4   Gain (%)  13.4

  • Mutations and SNPs (According to HGMD and SNP)

 

 
  • m-RNA                       (According to NCBI and CGAP)

 

  • mRNA sequence (Human):  NM_006088.5

  • Size: 1591bp

  • cDNA libraries:

  • Size: 445 amino acids: 49831 Da
  • Catalytic activity:
  • Subcellular domain:
  • Protein domains

     

  • Pathways and interactions (According to Kegg, IntAct)

 

  • Pathway:

     hsa04540  Gap junction
     hsa05130  Pathogenic Escherichia coli infection - EHEC
     hsa05131  Pathogenic Escherichia coli infection - EPEC

                        

 

  • Protein interactions: TUBB2C
  • Clinical                            (According to OMIM, PubMed)