• Alias                                 (According to NCBI)

• WIF-1

• Description   

  (According to SwissProt)

• Binds to WNT proteins and inhibits their activities. May be involved in mesoderm segmentation

• Chromosomal location

  (According to NCBI, CGH: progenetix)

• Location: 12q14.3
• Size: 70711 bp
• exons: 9
• DNA sequence (Human): NC_000012.10

• CGH (12q14.3):  Losses (%) -2.2   Gain (%)  8.9  

• Mutations and SNPs (According to HGMD and SNP)

• HGMD :
• SNPs: 11197

• m-RNA                       (According to NCBI and CGAP)

• mRNA sequence (Human):  NM_007191.3

• Size: 2026 bp

• cDNA libraries:

• Protein                        (According to SwissProt, Swiss2D, PDB, dbPTM)

• Size: 379 amino acids; 41528 Da
• Catalytic activity:

• Subcellular location: Secreted

• Protein domains

     

• Protein sequence (Human): Q9Y5W5

• Homologous genes:  31430

• 2D PAGE:

• 3D Structure:  2D3J

• PTM:  WIF1

 

• Pathways and interactions (According to BioCarta, DIP)

• Pathway:

          Wnt signaling pathway

• Protein interactions:

• Tissue

  (According to GeneNote, PubMed, HPA)

• Tissue expression: PubMed Reference
• Human Protein Atlas (HPA):  HPA039104

• Clinical                            (According to OMIM, PubMed)

• OMIM : 605186
• PubMed:    Early detection      Diagnosis         Prognosis        Therapy