WNT5A

(wingless-type MMTV integration site family, member 5A)

 

  • Alias                                 (According to NCBI)

 
  • hWNT5A
  • WNT-5A protein
  • Ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental protein. May be a signaling molecule which affects the development of discrete regions of tissues. Is likely to signal over only few cell diameters.
  • Location: 3p21-p14
  • Size: 21589 bp
  • exons:
  • DNA sequence (Human): NC_000003.10

  • CGH (3p21):  Losses (%) -29.6   Gain (%)  0.6  

  • Mutations and SNPs (According to HGMD and SNP)

 

 
  • m-RNA                       (According to NCBI and CGAP)

 

  • mRNA sequence (Human):  NM_003392.3

  • Size: 5855 bp

  • cDNA libraries:

  • Size: 365 amino acids: 40887 Da
  • Catalytic activity:

  • Subcellular location: Secreted, extracellular space, extracellular matrix.

  • Protein domains

     

  • Protein sequence (Human): P41221

  • Homologous genes:  20720

  • 2D PAGE:

  • 3D Structure:  

  • PTM: WNT5A

 
  • Pathways and interactions (According to  Kegg, IntAct)

 

                        

  • Protein interactions: WNT5A
  • Clinical                            (According to OMIM, PubMed)