APOL2

Apolipoprotein L, 2

 

  • Alias                                 (According to NCBI)

 
  • APOL-II
  • apolipoprotein L, 2
  • apolipoprotein L-II
  • Apolipoprotein L2 (Apolipoprotein L-II) (ApoL-II).

  • This gene is a member of the apolipoprotein L gene family. The encoded protein is found in the cytoplasm, where it may affect the movement of lipids or allow the binding of lipids to organelles. Two transcript variants encoding the same protein have been found for this gene.
  • Location: 22q12
  • Orientation: minus strand
  • Size: 13,745 bp
  • 7  exons
  • DNA sequence (Human):  NC_000022 

  • CGH (22q12):  Losses (%) -1.1  Gain (%)  15.1
  • Mutations and SNPs (According to HGMD and SNP)

 
  • m-RNA                       (According to NCBI and CGAP)

 
  • Size: 337 amino acids; 37092 Da
  • Catalytic activity:

  • Subcellular location: Cytoplasmic (Probable).

  • Protein domains

  • Pathways and interactions (According to BioCarta, DIP)

  • Pathway:

  • Protein interactions:

 
  • Clinical                            (According to OMIM, PubMed)