BAG1

                                                                                                     (BCL2-associated athanogene 1)

  • Alias                                 (According to NCBI)

 
  • BCL2-associated athanogene
  • BCL2-associated athanogene 1
  • H.sapiens mRNA for novel glucocorticoid receptor-associated protein
  • BAG-family molecular chaperone regulator-1 (BCL-2 binding athanogene- 1) (BAG-1) (Glucocorticoid receptor-associated protein RAP46).

  • The oncogene BCL2 is a membrane protein that blocks a step in a pathway leading to apoptosis or programmed cell death. The protein encoded by this gene binds to BCL2 and is referred to as BCL2-associated athanogene. It enhances the anti-apoptotic effects of BCL2 and represents a link between growth factor receptors and anti-apoptotic mechanisms.
  • Location: 9p12
  • Orientation: Minus strand
  • Size: 9,711 bases
  • 7 Exons
  • DNA Sequence: NT_008413

                 

  • CGH (9p12) :  Losses (%) -9.5   Gain (%)  6.1
  • Mutations and SNPs (According to HGMD and SNP)

 
  • m-RNA                       (According to NCBI and CGAP)

 
  • Size: 274 amino acids; 31117 Da
  • Protein domains:

                

  • Pathways and interactions (According to BioCarta, DIP)
  • Clinical                            (According to OMIM, PubMed)