CLDN17

Claudin 17

 

  • Alias                                 (According to NCBI)

 
  • claudin 17
  • human CLDN17 gene for claudin-17
  • Claudin-17. 3

  • Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity
  • Location: 21q22.11
  • Orientation: minus strand
  • Size: 674 bp
  • 1 exon
  • DNA sequence (Human): NC_000021

  • CGH (21q22.11):  Losses (%)  -15.6  Gain (%)  2.2  

  • Mutations and SNPs (According to HGMD and SNP)
  • HGMD (Human Gene Mutation Database):
  • SNPs: CLDN17

 
  • m-RNA                       (According to NCBI and CGAP)

 
  • Size: 224 amino acids; 24603 Da
  • Catalytic activity:

  • Subcellular location:  Integral membrane protein.

  • Protein domains

 
  • Pathways and interactions (According to Kegg, DIP)

  • Pathway:PATH: hsa04514  Cell adhesion molecules (CAMs)
    PATH: hsa04530  Tight junction
    PATH: hsa04670  Leukocyte transendothelial migration  

  • Protein interactions:
 

 
  • Clinical                            (According to OMIM, PubMed)