CTNNBIP1

                                                                                                                             ( Beta-catenin-interacting protein 1)

  • Alias                                 (According to NCBI)

 
  • ICAT
  • beta-catenin-interacting protein ICAT 
  • catenin, beta interacting protein 1 
  • catenin, beta-interacting protein 1
  • Beta-catenin-interacting protein 1 (Inhibitor of beta-catenin and Tcf- 4).
  • Prevents the interaction between CTNNB1 and TCF family members, and acts as negative regulator of the Wnt signaling pathway.
  • Location:1p36.22
  • Orientation: Minus strand
  • Size: 61,948 bases
  • 6 Exons
  • DNA Sequence: NT_021937

               

  • CGH (1p36.22):  Losses (%)  -1.7 Gain (%)  6.1 

 
  • Mutations and SNPs (According to HGMD and SNP)
  • m-RNA                       (According to NCBI and CGAP)

 
  • Size: 81 amino acids; 9170 Da
  • Sub cellular location: Nuclear and cytoplasmic
  • Protein domains:

               

 
  • Pathways and interactions (According to BioCarta, DIP)
  • Clinical                            (According to OMIM, PubMed)