ETS1

                                                                         (v-ets avian erythroblastosis virus E26 oncogene homolog 1)

  • Alias                                 (According to NCBI)

 
  • EWSR2
  • Avian erythroblastosis virus E26 (v-ets) oncogene homolog-1 
  • v-ets avian erythroblastosis virus E2 oncogene homolog 1
  • v-ets avian erythroblastosis virus E26 oncogene homolog 1
  • v-ets erythroblastosis virus E26 oncogene homolog 1 (avian) 
  • v-ets erythroblastosis virus E26 oncogene homolog 1 (avian)
  • C-ets-1 protein (p54).

  • It is a transcription factor. ETS is responsible for erythroblast and fibroblast transformation. The juxtaposition of the interferon and c-ETS-1 proto-oncogene may be involved in the pathogenesis of human monocytic leukemia.
  • Location:11q22.3
  • Orientation: Minus strand
  • Size: 60,774 bases
  • 8 Exons
  • DNA Sequence: NT_033899

            

  • CGH (11q22.3):  Losses (%)  -14.5 Gain (%)  8.4 

  • Mutations and SNPs (According to HGMD and SNP)
  • m-RNA                       (According to NCBI and CGAP)

 
  • Size: 441 amino acids; 50408 Da
  • Sub cellular location: Nuclear
  • Protein domains:

               

  • Pathways and interactions (According to BioCarta, DIP)
  • Clinical                            (According to OMIM, PubMed)