• Alias                                 (According to NCBI)

• HGNC:4141, 3' end
• G3PD
• G3PDH
• GAPDH
• glyceraldehyde-3-phosphate dehydrogenase .
• Glyceraldehyde-3-phosphate dehydrogenase, liver (EC 1.2.1.12) (GAPDH).
• Glyceraldehyde-3-phosphate dehydrogenase, muscle (EC 1.2.1.12) (GAPDH).

• Description   

  (According to SwissProt)

• Glyceraldehyde-3-phosphate dehydrogenase catalyzes an important energy-yielding step in carbohydrate metabolism, the reversible oxidative phosphorylation of glyceraldehyde-3-phosphate in the presence of inorganic phosphate and nicotinamide adenine dinucleotide (NAD). The enzyme exists as a tetramer of identical chains. A GAPD pseudogene has been mapped to Xp21-p11 and 15 GAPD-like loci have been identified

• Chromosomal location

  (According to NCBI, CGH: progenetix)

• Location: 12p13
• Orientation: plus strand
• Size: 3,879 bases
• 9  exons
• DNA sequence (Human): NC_000002

• CGH (12p13) : Losses (%)  -3.9 Gain (%)  10.1 

• Mutations and SNPs (According to HGMD and SNP)

• HGMD:
• SNPs: GAPD

• m-RNA                       (According to NCBI and CGAP)

• mRNA sequence (Human): NM_002046
• size :1283 bp
• cDNA Libraries : GAPD

• Protein                        (According to SwissProt, Swiss2D, PDB, dbPTM)

• Size: 334 amino acids; 35876 Da
• Catalytic activity: D-glyceraldehyde 3-phosphate + phosphate + NAD⁺ = 3-phospho-D-glyceroyl phosphate + NADH.

• Subcellular location: Cytoplasmic

• Protein domains

• Protein sequence (Human): P00354

• Homologous genes: GAPD

• 2D PAGE:P00354

• 3D Structure:1B7G

• PTM: GAPD

• Pathways and interactions (According to BioCarta, DIP)

• Pathways

         Downregulated of MTA-3 in ER-negative Breast Tumors

          Glycolysis Pathway   

• Protein interactions:

• Tissue

  (According to GeneNote, PubMed, HPA)

• Tissue expression: PubMed Reference
• Human Protein Atlas (HPA):

• Clinical                            (According to OMIM, PubMed)

• OMIM: 138400

• PubMed: Early detection      Diagnosis         Prognosis        Therapy