HGF
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- HPTA
- SF
- Hepatocyte growth factor (hepapoietin A; scatter factor)
- hepatopoietin A
- lung fibroblast-derived mitogen
- scatter factor
- Hepatocyte growth factor precursor (Scatter factor) (SF) (Hepatopoeitin
A).
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HGF is structurally similar, if not
identical, to scatter factor, a molecule shown to stimulate the dissociation and
scattering of epithelial cells. The sequence of HGF has about 35% identity to that of
plasminogen and the putative cleavage site of HGF is identical to that of plasminogen. A
potent mitogen for hepatocytes, HGF is also known as hepatopoietin A (HBGA)
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- Location: 7q21.1
- Orientation: Minus strand
- Size:71,099 bases
- 18 Exons
- DNA Sequence: NT_007933
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- Mutations and SNPs (According
to HGMD and SNP)
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- m-RNA Sequence: NM_000601
- Size: 2704 bp
- c-DNA Libraries: HGF
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- Size:728 amino acids; 83133 Da
- Protein domains:
- Protein sequence: P14210
- Homologous genes: HGF
- 2D PAGE:
- 3D Structure:2HGF
- PTM: HGF
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Signaling of Hepatocyte
Growth Factor Receptor
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