• Alias                                 (According to NCBI)

• 15-PGDH
• PGDH1
• hydroxyprostaglandin dehydrogenase 15-(NAD)
• 15-hydroxyprostaglandin dehydrogenase [NAD+] (EC 1.1.1.141) (PGDH).

• Description   

  (According to SwissProt)

         hydroxyprostaglandin dehydrogenase 15-(NAD)

• Chromosomal location

  (According to NCBI, CGH: progenetix)

• Location: 4q34-q35
• Orientation: minus strand
• Size: 32,258 bp
•  7  exons
• DNA sequence (Human):  NC_000004

• CGH (4q34-35):  Losses (%) -19.6  Gain (%) 0.6  

• Mutations and SNPs (According to HGMD and SNP)

• HGMD:
• SNPs: HPGD

• m-RNA                       (According to NCBI and CGAP)

• mRNA sequence (Human): NM_000860

• Size: 2592 bp

• cDNA libraries: HPGD

• Protein                        (According to SwissProt, Swiss2D, PDB, dbPTM)

• Size: 266 amino acids; 28977 Da
• Catalytic activity: (5Z,13E)-(15S)-11-alpha,15-dihydroxy-9-oxoprost-13-enoate + NAD⁺ = (5Z,13E)-11-alpha-hydroxy-9,15-dioxoprost-13-enoate + NADH.

• Subcellular location: Cytoplasmic.

• Protein domains

• Protein sequence (Human): P15428

• Homologous genes: HPGD

• 2D PAGE: P15428

• 3D Structure:

• PTM: HPGD

• Pathways and interactions (According to BioCarta, DIP)

• Pathway:

• Protein interactions:

• Tissue

  (According to GeneNote, PubMed, HPA)

• Tissue expression: PubMed Reference
• Human Protein Atlas (HPA): HPA004919

• Clinical                            (According to OMIM, PubMed)

• OMIM: 601688

• PubMed: Early detection      Diagnosis         Prognosis        Therapy