ICAM1

                                                                                 (Intercellular adhesion molecule 1)

  • Alias                                 (According to NCBI)

 

  • BB2 
  • CD54
  • cell surface glycoprotein P3.58
  • intercellular adhesion molecule 1 (CD54), human rhinovirus receptor
  • Intercellular adhesion molecule-1 precursor (ICAM-1) (Major group rhinovirus receptor) (CD54 antigen)
  • ICAM1 (CD54) is typically expressed on endothelial cells and cells of the immune system. ICAM1 binds to integrins of type CD11a / CD18, or CD11b / CD18. ICAM1 is also exploited by Rhinovirus as a receptor.
  • Location: 19p13.3-p13.2
  • Orientation: Plus strand
  • Size: 15,527 bases
  • 7 Exons
  • DNA Sequence: NT_011295

                         

 

  • CGH (19p13.3-13.3):  Losses (%)  -2.8 Gain (%)  14.0 

  • Mutations and SNPs (According to HGMD and SNP)
  • m-RNA                       (According to NCBI and CGAP)

 

  • Size:532 amino acids; 57826 Da
  • Sub cellular location: Type I membrane protein
  • Protein domains:

              

  • Pathways and interactions (According to BioCarta, DIP)
  • Clinical                            (According to OMIM, PubMed)