ID3

                                                                               (DNA-binding protein inhibitor ID-3)

  • Alias                                 (According to NCBI)

 

  • 1R21 (SP)
  • HEIR-1 (LL)
  • inhibitor of DNA binding 3, dominant negative helix-loop-helix protein (GDB, SP, HUGO)
  • DNA-binding protein inhibitor ID-3 (ID-like protein inhibitor HLH 1R21) (Helix-loop-helix protein HEIR-1)
  • Members of the ID family of helix-loop-helix (HLH) proteins lack a basic DNA-binding domain and inhibit transcription through formation of nonfunctional dimers that are incapable of binding to DNA.
  • Location: 1p36.13-p36.12
  • Orientation: Minus strand
  • Size: 1,829 bases
  • 3 Exons
  • DNA Sequence: NT_004610

                

  • CGH (1p36.13-36.12):  Losses (%)  -1.7 Gain (%)  4.5 

  • Mutations and SNPs (According to HGMD and SNP)
  • HGMD:
  • SNPs: ID3
  • m-RNA                       (According to NCBI and CGAP)

 

  • Size:119 amino acids; 12969 Da
  • Sub cellular location: Nuclear
  • Protein domains:

              

          

  • Protein sequence:Q02535
  • Homologous genes: ID3
  • 2D PAGE:
  • 3D Structure:
  • PTM: ID3
  • Pathways and interactions (According to BioCarta, DIP)
  • Clinical                            (According to OMIM, PubMed)