IGKC

(Immunoglobulin Kappa Constant)

 

  • Alias                                 (According to NCBI)

 
  • HCAK1
  • Km 
  • Immunoglobulin kappa constant
  • immunoglobulin kappa constant region 
  • kappa 1 immunoglobulin light chain 
  • Ig kappa chain C region
  • Receptor for EGF, but also for other members of the EGF family, as TGF-alpha, amphiregulin, betacellulin, heparin-binding EGF-like growth factor, GP30 and vaccinia virus growth factor. Is involved in the control of cell growth and differentiation.
  • Location: 2p12
  • Orientation: minus strand
  • Size:  323 bp
  • ------exons
  • DNA sequence (Human): NC_000002.

 

  • CGH (2p12):  Losses (%) -1.7    Gain (%) 4.5  

  • Mutations and SNPs (According to HGMD and SNP)
  • m-RNA                       (According to NCBI and CGAP)

 

  • mRNA sequence (Human):

  • Size:

  • cDNA libraries: IGKC
  • Size: 106 aa , 11609 Da
  • Catalytic activity:

  • Subcellular location:

  • Protein domains

        

  • Pathways and interactions (According to BioCarta, DIP)

  • Pathway:

  • Protein interactions:
  • Clinical                            (According to OMIM, PubMed)