ITGA5

                                                                                                   (Integrin, alpha 5)

Alias                                 (According to NCBI)	CD49f integrin, alpha 5 Integrin alpha-5 precursor (VLA-5A) (CD49e) integrin alpha-F
Description    (According to SwissProt)	Integrin alpha-5/beta-1 is a receptor for fibronectin and fibrinogen. It recognizes the sequence R-G-D in its ligands. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions.
Chromosomal location (According to NCBI, CGH: progenetix)	Location:12q11-q13 Orientation: Plus strand Size:24006 bases 30 Exons DNA Sequence: NC_000012               CGH (12q11):  Losses (%) -0.6  Gain (%)  5.0
Mutations and SNPs (According to HGMD and SNP)	HGMD: SNPs: ITGA5
m-RNA                       (According to NCBI and CGAP)	m-RNA Sequence: NM_002205 Size:4267 bp c-DNA Libraries: ITGA6
Protein                        (According to SwissProt, Swiss2D, PDB, dbPTM)	Size: 1049 amino acids; 114536 Da Sub cellular location: Type I membrane protein. membrane Protein domains:                Protein sequence: P08648 Homologous genes: 2D PAGE: 3D Structure: PTM: ITGA5
Pathways and interactions (According to BioCarta, DIP)	Pathways: Interactions: ITGA5
Tissue (According to GeneNote, PubMed, HPA)	Tissue expression: PubMed Reference Human Protein Atlas (HPA): HPA002642
Clinical                            (According to OMIM, PubMed)	OMIM:135620 PubMed: Early detection      Diagnosis         Prognosis        Therapy