• Alias                                 (According to NCBI)

• GBP
• galectin
• Lectin, galactose-binding, soluble, 1
• lectin, galactoside-binding, soluble, 1 (galectin 1)
• Galectin-1 (Beta-galactoside-binding lectin L-14-I) (Lactose-binding lectin 1) (S-Lac lectin 1)
  (Galaptin) (14 kDa lectin) (HPL) (HBL).

• Description   

  (According to SwissProt)

• The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. LGALS1 may act as an autocrine negative growth factor that regulates cell proliferation.

• Chromosomal location

  (According to NCBI, CGH: progenetix)

• Location: 22q13.1
• Orientation: plus strand
• Size: 4,194 bases
• 4 exons
• DNA sequence (Human):  NC_000022.

·         CGH (22q13.1):  Losses (%)  -1.1   Gain (%)   15.1  

• Mutations and SNPs (According to HGMD and SNP)

• HGMD:
• SNPs: LGALS1

• m-RNA                       (According to NCBI and CGAP)

• mRNA sequence (Human): NM_002305.
•   Size: 526 bp
• cDNA libraries: LGALS1

• Protein                        (According to SwissProt, Swiss2D, PDB, dbPTM)

• Size: 134 amino acids; 14584 Da
• Catalytic activity:

·         Subcellular location: plasma membrane

·         Protein domains

·         Protein sequence (Human): P09382

·         Homologous genes: LGALS1

·         2D PAGE:P09382

·         3D Structure: 1GZW

• PTM: LGALS1

• Pathways and interactions (According to BioCarta, DIP)

·         Pathway:

·         Protein interactions:

• Tissue

  (According to GeneNote, PubMed, HPA)

• Tissue expression: PubMed Reference
• Human Protein Atlas (HPA): HPA000646

• Clinical                            (According to OMIM, PubMed)

· OMIM: 150570

PubMed:    Early detection      Diagnosis         Prognosis        Therapy