MST1R
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- CDw136
- RON
- macrophage stimulating 1 receptor (c-met-related tyrosine kinase)
- Macrophage-stimulating protein receptor precursor (EC 2.7.1.112) (MSP
receptor) (p185-Ron) (CDW136) (CD136 antigen)
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- It is the receptor for macrophage stimulating protein (MSP) and has a tyrosine-protein
kinase activity. It is predominantly expressed in keratinocytes and lung.
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- Location: 3p21.3
- Orientation: Minus strand
- Size: 16,632 bases
- 20 Exons
- DNA Sequence: NT_022517
- CGH (3p21.3): Losses (%) -29.1 Gain
(%) 0.6
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- Mutations and SNPs (According
to HGMD and SNP)
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- m-RNA Sequence: NM_002447
- Size:
4541 bp
- c-DNA Libraries: MST1R
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- Size:1400 amino acids; 152227 Da
- Sub cellular location: Type I membrane protein
- Catalytic activity: ATP + a protein tyrosine = ADP + protein tyrosine phosphate
- Protein domains:
- Protein sequence: Q04912
- Homologous genes: MST1R
- 2D PAGE:
- 3D Structure:
- PTM: MST1R
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