MYL1

(Mylosin Light Chain 1)

 

  • Alias                                 (According to NCBI)

 
  • MLC1F 2
  • MLC3F 2
  • A1 catalytic 2
  • A2 catalytic 2
  • myosin, light polypeptide 1, alkali; skeletal, fast 1, 2, 5
  • Myosin light chain 3, skeletal muscle isoform (A2 catalytic) (Alkali myosin light chain 3)
    (MLC3F). 3
  • Myosin light chain 1, skeletal muscle isoform (MLC1F) (A1 catalytic) (Alkali myosin light chain
    1). 3
  • Myosin is a hexameric ATPase cellular motor protein. It is composed of two heavy chains, two nonphosphorylatable alkali light chains, and two phosphorylatable regulatory light chains. This gene encodes a myosin alkali light chain expressed in fast skeletal muscle. Two transcript variants have been identified for this gene.
  • Location: 2q33-q34
  • Orientation: minus strand
  • Size: 25,021 bp
  • 9 exons
  • DNA sequence (Human): NC_000002

 

 

  • CGH (2q33-34):  Losses (%) -5.6   Gain (%)  7.3  
  • Mutations and SNPs (According to HGMD and SNP)
  • m-RNA                       (According to NCBI and CGAP)

 
  • Size: 193 amino acids; 21014 Da
  • Catalytic activity:
  • Subcellular location:
  • Protein domains

 

      

           

  • Pathways and interactions (According to BioCarta, DIP)

  • Pathway:

  • Protein interactions:

                     

 

 

 

 
  • Clinical                            (According to OMIM, PubMed)