PLAG1

                                                                                            (pleomorphic adenoma gene-1)

Alias                                 (According to NCBI)	LOT1  ZAC  ZAC1 Human LOT1 mRNA, complete cds PLAG-like 1 ZAC tumor supressor  pleiomorphic adenoma gene-like 1 pleomorphic adenoma gene-like 1 Zinc finger protein PLAGL1 (Pleiomorphic adenoma-like protein 1)
Description    (According to SwissProt)	This gene encodes a C2H2 zinc finger protein with transactivation and DNA-binding activity. This gene has been shown to exhibit antiproliferative activities and is a tumor suppressor gene candidate.
Chromosomal location (According to NCBI, CGH: progenetix)	Location: 8q12 Orientation: Minus strand Size: 68,116 bases 6 Exons DNA Sequence: NT_025741 CGH (8q12):  Losses (%) - 0.0   Gain (%)  25.7
Mutations and SNPs (According to HGMD and SNP)	HGMD : SNPs: PLAG1
m-RNA                       (According to NCBI and CGAP)	m-RNA Sequence: 2 Transcript variants:NM_002656, NM_006718 c-DNA Libraries: PLAG1
Protein                        (According to SwissProt, Swiss2D, PDB, dbPTM)	Size: 411 amino acids; 44652 Da Catalytic activity: Sub cellular location: Nuclear Protein domains:                                                     Protein sequence: Q9UM63 Homologous genes: PLAG1 2D PAGE: 3D Structure: PTM: PLAG1
Pathways and interactions (According to BioCarta, DIP)	Pathways: Interactions:
Tissue (According to GeneNote, PubMed, HPA)	Tissue expression: PubMed Reference Human Protein Atlas (HPA): HPA005462
Clinical                            (According to OMIM, PubMed)	OMIM:603044 PubMed:    Early detection      Diagnosis         Prognosis        Therapy