RRAS

 (Related  RAS Viral (R-RAS) Oncogene Homolog)

 

  • Alias                                 (According to NCBI)

 
  • Oncogene RRAS
  • RAS-RELATED PROTEIN R-RAS
  • related RAS viral (r-ras) oncogene homolog
  • Ras-related protein R-Ras (p23).
  • related RAS viral (r-ras) oncogene homolog

  • CGH (19q13.3):  Losses (%) - 2.8   Gain (%)  10.1  

  • Mutations and SNPs (According to HGMD and SNP)
  • m-RNA                       (According to NCBI and CGAP)

 

  • mRNA sequence (Human): NM_006270

  • Size: 1017 bp

  • cDNA libraries: RRAS
  • Size: 218 amino acids; 23480 Da
  • Catalytic activity:

  • Subcellular location: Inner surface of plasma membrane possibly with attachment requiring acylation of the C-terminal cysteine (By similarity with RAS).

  • Protein domains


  • Pathways and interactions (According to BioCarta, DIP)

  • Pathway:

  1. Cycling of Ran in nucleocytoplasmic transport

  2. Phosphoinositides and their downstream targets

  3. Rab GTPases Mark Targets In The Endocytotic Machinery

  4. The role of FYVE-finger proteins in vesicle transport

  • Protein interactions:

 

  • Clinical                            (According to OMIM, PubMed)