S100A4

                                                                         (S100 calcium-binding protein A4)

  • Alias                                 (According to NCBI)

 
  • 18A2 
  • 42A 
  • CAPL
  • MTS1
  • P9KA
  • PEL98
  • PLACENTAL CALCIUM-BINDING PROTEIN
  • S100 calcium binding protein A4 (calcium protein, calvasculin, metastasin, murine placental homolog)
  • S100 calcium-binding protein A4 (calcium protein, calvasculin, metastasin, murine placental homolog) 
  • malignant transformation suppression 1
  • Placental calcium-binding protein (Calvasculin) (S100 calcium-binding protein A4) (MTS1 protein).

  • The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in motility, invasion, and tubulin polymerization. Chromosomal rearrangements and altered expression of this gene have been implicated in tumor metastasis.
  • Location:1q21
  • Orientation: Minus strand
  • Size: 201,216 bases
  • 3 Exons
  • DNA Sequence: NT_079484

  • CGH (1q21):  Losses (%) - 1.1   Gain (%)  7.8  

  • Mutations and SNPs (According to HGMD and SNP)
  • HGMD :
  • m-RNA                       (According to NCBI and CGAP)

 
  • Size: 101 amino acids; 11728 Da
  • Catalytic activity:
  • Subcellular location:
  • Protein domains:

                                                      
  • Pathways and interactions (According to BioCarta, DIP)
  • Pathways:
  • Interactions:
  • Clinical                            (According to OMIM, PubMed)