S100A9

(S100  Calcium Binding Protein  A9 (calgranulin B))

 

  • Alias                                 (According to NCBI)

 

  • 60B8AG
  • CAGB
  • CFAG 
  • CGLB 
  • L1AG 
  • LIAG 
  • MAC387 
  • MIF 
  • MRP14 
  • NIF
  • S100 calcium binding protein A9 (calgranulin B) 
  • S100 calcium-binding protein A9 (calgranulin B) 
  • Calgranulin B (Migration inhibitory factor-related protein 14) (MRP- 14) (P14) (Leukocyte L1
    complex heavy chain) (S100 calcium-binding protein A9) (Calprotectin L1H subunit).

 

  • The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in the inhibition of casein kinase and altered expression of this protein is associated with the disease cystic fibrosis
  • Location: 1q21
  • Orientation: plus strand
  • Size: 3169 bp
  • 3 exons
  • DNA sequence (Human): NC_000001.

 

  • CGH (1q21):  Losses (%) - 1.1   Gain (%)  7.8  

  • Mutations and SNPs (According to HGMD and SNP)

 

  • m-RNA                       (According to NCBI and CGAP)

 

 

·         Protein domains

 

·         Protein sequence (Human): P06702

 

 

  • Pathways and interactions (According to BioCarta, DIP)

·         Pathway:

·         Protein interactions: 

 

 

 

  • Clinical                            (According to OMIM, PubMed)