SDC1

                                                                                                            (Syndecan 1)

  • Alias                                 (According to NCBI)

 

  • CD138 
  • SDC 
  • SYND1 
  • syndecan 1
  • Syndecan-1 precursor (SYND1) (CD138 antigen)
  • Syndecan, a cell surface proteoglycan, is an integral membrane protein acting as a receptor for the extracellular matrix. It is 1 of a group of transmembrane heparin sulfate proteoglycans. Homologs of the human syndecan gene have been identified in mouse, rat, and Chinese hamster

  • Location:2p24.1
  • Orientation: Minus strand
  • Size: 24,314 bases
  • 5 Exons
  • DNA Sequence: NT_015926

  • CGH (2p24.1):  Losses (%) - 2.8   Gain (%)  5.0  

  • Mutations and SNPs (According to HGMD and SNP)
  • HGMD :

 

  • m-RNA                       (According to NCBI and CGAP)

 

  • Size:310 amino acids; 32476 Da
  • Catalytic activity:
  • Sub cellular location: Type I membrane protein
  • Protein domains:

                                                               

  • Protein sequence: P18827
  • Homologous genes: SDC1
  • 2D PAGE:
  • 3D Structure:
  • PTM: SDC1
  • Pathways and interactions (According to BioCarta, DIP)
  • Pathways:
  • Interactions: 1123N
  • Clinical                            (According to OMIM, PubMed)