• Alias                                 (According to NCBI)

• TPI
• TPI
•  MGC88108
• triosephosphate isomerase 1
• Triosephosphate isomerase (EC 5.3.1.1) (TIM) (Triose-phosphate isomerase).

• Description   

  (According to SwissProt)

• Basic function  is catalyzing the aldose-ketose isomerization of dihydroxyacetone phosphate and glyceraldehyde 3-phosphate.

• Chromosomal location

  (According to NCBI, CGH: progenetix)

• Location: 12p13.31
• Orientation: plus strand
• Size: 3,299 bases
• 7 exons
• DNA sequence (Human):  NC_000012

CGH (12p13.21): Losses (%) -3.9   Gain (%)  8.9  

• Mutations and SNPs  (According to HGMD and SNP)

• HGMD: TPI1

• SNPs: TPI1

• m-RNA                           (According to NCBI and CGAP)

• mRNA sequence (Human): : NM_000365

• Size: 1254bp

• cDNA libraries: TPI1

• Protein                                  (According to SwissProt, Swiss2D, PDB, dbPTM)

• Size: 248 amino acids; 26538 Da
• Catalytic activity: D-glyceraldehyde 3-phosphate = glycerone phosphate.

·         Subcellular location:

·         Protein domains

·         Protein sequence (Human): P60174

·         Homologous genes: TPI1

·         2D PAGE: P60174

·         3D Structure: 1HTI

          PTM: TPI1

• Pathways and interactions (According to BioCarta, DIP)

• Pathway:

          Glycolysis Pathway

• Protein interactions:

• Tissue

  (According to GeneNote, PubMed, HPA)

• Tissue expression: PubMed Reference
• Human Protein Atlas (HPA) : CAB004675

• Clinical                            (According to OMIM, PubMed)

• OMIM: 190450

• PubMed:  Early detection      Diagnosis      Prognosis      Therapy