VDAC2

                                                                              (Voltage-dependent anion channel 2)

Alias                                 (According to NCBI)	voltage-dependent anion channel 2 Voltage-dependent anion-selective channel protein 2 (VDAC-2) (hVDAC2) (Outer mitochondrial membrane protein porin 2).
Description    (According to SwissProt)	Forms a channel through the mitochondrial outer membrane that allows diffusion of small hydrophilic molecules. The channel adopts an open conformation at low or zero membrane potential and a closed conformation at potentials above 30-40 mV. The open state has a weak anion selectivity whereas the closed state is cation- selective.
Chromosomal location (According to NCBI, CGH: progenetix)	Location: 10q22 Orientation: Plus strand Size: 59,484 bases 10 Exons DNA Sequence: NT_008583 CGH (10q22): Losses (%) -7.8   Gain (%)  2.8
Mutations and SNPs  (According to HGMD and SNP)	HGMD: SNP: VDAC2
m-RNA                           (According to NCBI and CGAP)	m-RNA Sequence: NM_003375 Size: 1522 bp c-DNA Libraries: VDAC2
Protein                                  (According to SwissProt, Swiss2D, PDB, dbPTM)	Size: 347 amino acids; 38092 Da Catalytic activity: Sub cellular location: Outer mitochondrial membrane. Protein domains:                             Protein sequence: P45880 Homologous genes: VDAC2 2D PAGE: 3D Structure: PTM: VDAC2
Pathways and interactions (According to BioCarta, DIP)	Pathways: Interactions:
Tissue (According to GeneNote, PubMed, HPA)	Tissue expression: PubMed Reference Human Protein Atlas (HPA) : VDAC2
Clinical                            (According to OMIM, PubMed)	OMIM:193245 PubMed:  Early detection      Diagnosis      Prognosis      Therapy