VEGFB

                                                     (vascular endothelial growth factor B)

  • Alias                                 (According to NCBI)

 

  • VEGFL
  • VRF
  • vascular endothelial growth factor B
  • Vascular endothelial growth factor B precursor (VEGF-B) (VEGF related factor) (VRF).
  • Growth factor for endothelial cells. VEGF-B167 binds heparin and neuropilin-1 whereas the binding to neuropilin-1 of VEGF-B186 is regulated by proteolysis.
  • Location:11q13
  • Orientation: Plus strand
  • Size:3,995 bases
  • 7 Exons
  • DNA Sequence:NT_033903

  • CGH (11q13): Losses (%) -3.4   Gain (%)  13.4  

  • Mutations and SNPs  (According to HGMD and SNP)

 

  • m-RNA                           (According to NCBI and CGAP)

 

 
  • Location: 11q13
  • Catalytic activity:
  • Sub cellular location: Secreted but remains associated to cells or to the extra cellular matrix
    unless released by heparin.
  • Protein domains:
     

                                     

               

  • Pathways and interactions (According to BioCarta, DIP)
  • Pathways:
  • Interactions: P49765
   
  • Clinical                            (According to OMIM, PubMed)