Principal Investigator

RESEARCH

Brain tumours are one of the leading causes of cancer related deaths. Glioblastoma (GBM) and Medulloblastoma are two high grade malignant brain tumours that differ strikingly in their clinical behaviour and underlying biology. they have been using high throughput genomic technologies to identify genetic alterations and delineate their role in pathogenesis of medulloblastomas. While the genetic alterations in GBMs are largely understood, their complexity accompanied by the intrinsic resistance and invasive potential of GBMs poses enormous challenge to identification of therapeutic targets in GBMs. They have been investigating the molecular basis of the intrinsic resistance of GBM cells to cell death.