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Research Projects

Molecular imaging of cancer stem cells (CSCs) during development of chemo resistance in ovarian carcinoma


Cancer Stem Cells, a small population residing within the tumor bulk are inherently chemoresistant in nature and the major cause behind tumor relapse. Previously we have shown modulation in IGF-1R-Akt axis is associated with development of chemoresistance in ovarian cancer cells (Singh et. al., 2014). Currently I am trying to investigate the role of IGF-1R-Akt signaling in Cancer Stem Cell phenotype and function during acquirement of chemoresistance.

Usha Patel

Senior Research Fellow

Ram Kumar Singh

Ray Lab

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