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Advanced Centre for Treatment Research & Education in Cancer
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Science Sparks @ ACTREC
Date Image 11th October 2021 Vol. No. 10; Issue No. 496

1. Bajpai J, Pradeep V, Joshi S, Wadasadawala T, Rath S, Pathak R, Nandhara R, Mohanty S, Chougle Q, Engineer M, Abraham N, Ghosh J, Nair N, Gulia S, Popat P, Patil A, Sheth T, Desai S, Thakur M, Rangrajan V, Parmar V, Sarin R, Gupta S, Badwe R (2021). Unique challenges and outcomes of young women with breast cancers from a tertiary care cancer centre in India. The Breast.

2. Gupta S, Biswas G, Babu S, Maksud T, Lakshmaiah K, Patel J, Raja G, Boya R, Patil P, Choudhury K, Bondare S, Neve R, Bhat G, Mamillapalli G, Patel A, Patel P, Joshi N, Bajaj V, Khan M (2021). Fixed dose combination of capecitabine and cyclophosphamide in metastatic breast cancer: Results from THE ENCLOSE phase 2/3 randomized multicenter study. The Breast. 60: 147-154.

3. Fundytus A, Sengar M, Lombe D, Hopman W, Jalink M, Gyawali B, Trapani D, Roitberg F, De Vries EGE, Moja L, Ilbawi A, Sullivan R, Booth CM (2021). Access to cancer medicines deemed essential by oncologists in 82 countries: an international, cross-sectional survey. Lancet Oncology. 22(10):1367-1377.

4. Shetty O, Gurav M, Bapat P, Karnik N, Wagh G, Pai T, Epari S, Desai S (2021). Moving Next-Generation Sequencing into the Clinic. Indian Journal of Medical and Paediatric Oncology. 42(3): 221-228.

5. Reddy D, Bhattacharya S, Shah S, Rashid M, Gupta S (2021). DNA methylation mediated downregulation of histone 53 variant H3.3 affects cell proliferation contributing to the development of HCC.Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease.

6. Tilwani S, Gandhi K, Narayan S, Ainavarapu SRK, Dalal SN (2021). Disruption of desmosome function leads to increased centrosome clustering in 14-3-3γ-knockout cells with supernumerary centrosomes. FEBS Letters.

7. Nikam SS, Gurjar M, Singhavi H, Patil A, Singh A, Villalta P, Chaturvedi P, Khariwala SS, Gota V, Stepanov I (2021). Simultaneous analysis of urinary total 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol, N'-nitrosonornicotine, and cotinine by liquid chromatography-tandem mass-spectrometry. Scientific Reports. 11(1):20007.

8. Sajnani AK, Shah SG, Rashid M, Natu A, Gera PB, Gupta S (2021). In-Silico Analysis of Chromatin Modifiers and Profiling of Histone Deacetylases (HDAC's) in Human Oral Cancer. Chonnam Medical Journal. 57(3):176-184.

9. Noguera N, Hasan S, Ammatuna E, Venditti A (2021). Metabolic rewiring in leukemias. Frontiers in Oncology. 11: 775167.

Book Chapter

Gupta C, Uthale A, Teni T, Ambre P, Coutinho E. "Emerging Polymer-Based Nanomaterials for Cancer Therapeutics". In: Saravanan M, Barabadi H. (Eds) Cancer Nanotheranostics. Nanotechnology in the Life Sciences. Cham:Springer, 2021. (ISBN: 978-3-030-74329-1)

Site of the Week

DataBase of CpG islands and Analytical Tool (DBCAT) is developed in order to recognize comprehensive mehtylation profiles of DNA alteration in human cancer.

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Interesting Reads

Satcher RL, Zhang XH. Evolving cancer-niche interactions and therapeutic targets during bone metastasis. Nat Rev Cancer. 2021.

Legends of Science
Makund Behari Lal Makund Behari Lal

Makund Behari Lal obtained his DSc from the University of Lucknow in 1937 and another DSc from the University of Edinburgh in 1947. He made significant contributions to the morphology and taxonomy of trematode parasites and larval helminthus. He revised classification of genus Helminthus parasites on the basis of detailed morphological and anatomical studies. He also did in vitro and biochemical investigations on the parasites. He was the Director, Dayalbagh Education Institute, Agra; Professor of Zoology, Dean of Science and Vice-Chancellor, University of Lucknow. Dr. Lala was the fellow of Indian Academy of Sciences, Bangalore; President, Lucknow University Research Society; Vice-President, International Congress of Zoology, London in 1958; Chairman, International Congress of History of Science, Cornell and Philadelphia in 1962.

Sivatosh Mookerjee Sivatosh Mookerjee

Sivatosh Mookerjee secured his PhD from the University of Edinburgh, UK in 1951 with specialization in Development Biology. He did research on molecular nature of subcellular and cellular restructurations of lower eukaryotes. His studies on molecular and cellular basis of cell recognition and cell interactions in sponges revealed the principles underlying the process of cell replacement in regeneration, cell association and its probable role in the evolution of multicellularity. His work on amphibian and chick embryos gave a new sight into pattern-building mechanisms. He was the Dean, School of life sciences, JNU, New Delhi. Dr. Mookerjee was the recipient of the Sir Dorab Tata Gold Medal in 1962, BC Roy Memorial Oration Gold Medal in 1980.

Do You Know?

In 2015, A study of colorectal cancer genomics puts forward a model of tumour evolution whereby tumour growth is predominantly driven by an early, mutational ‘Big Bang’ which produces numerous clones, none of which are subject to stringent selection.

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Cancer News
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Maharashtra CM opens Infy Foundation's Asha Nivas Dharamshala at Tata Memorial Centre Campus

08 October 2021, The Economic Times

Infosys Foundation, the CSR arm of software giant Infosys on Thursday announced the launch of the ‘Infosys Foundation Asha Nivas Dharamshala’ (rest house), at The Advanced Centre for Treatment, Research and Education in Cancer (ACTREC) campus of Tata Memorial Centre, in Navi Mumbai...

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