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Advanced Centre for Treatment Research & Education in Cancer
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Science Sparks @ ACTREC
Date Image 13th December 2021 Vol. No. 10; Issue No. 505

1. Laskar SG, Sinha S, Singh M, Mummudi N, Mittal , Gavarraju A, Budrukkar A, Swain M, Agarwal JP, Gupta T, Murthy V, Mokal S, Patil V, Noronha V, Joshi A, Menon N, Prabhash K (2021). Post-cricoid and upper oesophagus cancers treated with organ preservation using intensity-modulated image-guided tadiotherapy: A Phase II prospective study of outcomes, toxicity and quality of life. Clinical Oncology.

Site of the Week

DepMap is a comprehensive preclinical reference portal that connects tumor features with genetic and small molecule dependencie.

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Interesting Reads

Good CR, Aznar MA, Kuramitsu S, Samareh P, Agarwal S, Donahue G, Ishiyama K, Wellhausen N, Rennels AK, Ma Y, Tian L, Guedan S, Alexander KA, Zhang Z, Rommel PC, Singh N, Glastad KM, Richardson MW, Watanabe K, Tanyi JL, O'Hara MH, Ruella M, Lacey SF, Moon EK, Schuster SJ, Albelda SM, Lanier LL, Young RM, Berger SL, June CH (2021). An NK-like CAR T cell transition in CAR T cell dysfunction. Cell. 25: 6081-6100.

Legends of Science
Thammajirao Ramchandran Rao Thammajirao Ramchandran Rao

Thammajirao Ramchandran Rao obtained his DSc from the University of Kolkata in 1961. His specialization was in anopheles mosquitoes and measures for controlling malaria in rural area. His study included the epidemiology of vector-borne diseases and viruses and morphology of grasshoppers' chromosomes. Dr. Rao was Director, Virus Research Centre, Pune. He was President, Zoology Section, Indian Science Congress in 1972. He was a Fellow of the National Academy of Medical Sciences, National Society of Communicable Diseases, Royal Society of Tropical Medicine and Hygiene. He was also an Honorary Member of the American Society of Tropical Medicine and Hygiene.

Subhash Mukhopadhyay Subhash Mukhopadhyay

Subhash Mukhopadhyay obtained his Ph.D. from the University of Kolkata in 1958 and specialized in Reproductive Endocrinology. He became the first physician in India to perform In-vitro fertilization resulting in a test tube baby in October 1978. Dr. Mukhopadhyay's name is included in 'The Dictionary of Medical Biography’ published by the World Foundation, which enlists 1100 medical scientists from 100 countries around the world for their pathbreaking contributions to Medical Science.

Do You Know?

In 2016, FDA approved atezolizumab(Tecentriq) for advanced urothelial carcinoma, the most common form of bladder cancer.

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Cancer News
Connecting the dots to find new treatments for breast cancer

07 December 2021, EurekAlert

Basal-like tumours are the most aggressive type of breast cancer, with the worst prognosis. Chemotherapy is the only available treatment option, but patients experience high recurrence rates...

Test detects early signs of remaining cancer in kids treated for medulloblastoma

08 December 2021, National Cancer Institute

Researchers have developed a test that detects specific changes in DNA fragments, or cell-free DNA, shed from medulloblastoma tumor cells into the fluid surrounding the brain and spinal cord, known as the cerebrospinal fluid...

Measuring cancer cell state can reveal drug susceptibility

09 December 2021, ScienceDaily

Pancreatic cancer cells can exist in, and transition between, three different cell states, according to new research. These states respond differently to a variety of cancer drugs, and altering the tumor microenvironment can drive tumor cells from one state to another, potentially offering a way to make them more susceptible to a particular drug...

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